{"id":2578,"date":"2023-01-04T18:25:58","date_gmt":"2023-01-04T18:25:58","guid":{"rendered":"https:\/\/cafeprosaedicas.com.br\/?p=2578"},"modified":"2023-04-08T16:46:23","modified_gmt":"2023-04-08T16:46:23","slug":"complicacoes-tardias-no-paciente-com-deficiente-g6pd-por-dr-sergio-augusto","status":"publish","type":"post","link":"https:\/\/cafeprosaedicas.com.br\/?p=2578","title":{"rendered":"Complica\u00e7\u00f5es Tardias No Paciente Com Deficiente G6PD: Por Dr S\u00e9rgio Augusto"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2578\" class=\"elementor elementor-2578\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5c03148 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5c03148\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f180a37\" data-id=\"f180a37\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b936dc4 elementor-widget elementor-widget-text-editor\" data-id=\"b936dc4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Uma d\u00favida muito frequente para os pais de portadores da Defici\u00eancia de\u00a0 G6PD \u00e9: se eu n\u00e3o seguir as restri\u00e7\u00f5es ou quando ele crescer e n\u00e3o quiser seguir, quais s\u00e3o os riscos?<\/p><p>Em primeiro lugar devemos ter sempre em mente que a defici\u00eancia de G6PD \u00e9 colocada no grupo de anemias hemol\u00edticas, portanto n\u00e3o seguir as recomenda\u00e7\u00f5es pode levar a hem\u00f3lise aguda.<\/p><p>Nos epis\u00f3dios agudos, teremos um sofrimento de diversos setores (c\u00e9rebro, pele, pulm\u00e3o, cora\u00e7\u00e3o, rins) esse sofrimento vai causar sobrecarga do f\u00edgado e ba\u00e7o e assim determinar efeitos futuros. Quando um paciente sofre hem\u00f3lise, o ba\u00e7o \u00e9 \u00f3rg\u00e3o respons\u00e1vel por fazer a \u201climpeza\u201d das c\u00e9lulas quebradas, com isso ele precisa aumentar sua capacidade de trabalho, aumentando de tamanho para dar conta do servi\u00e7o. No caso do f\u00edgado ele come\u00e7a a ter mais trabalho para metabolizar subst\u00e2ncias, o que pode levar a seu aumento tamb\u00e9m durante a hem\u00f3lise.<\/p><p>Se tivermos v\u00e1rios epis\u00f3dios semelhantes ao longo da vida teremos um ba\u00e7o com maior volume de sangue, com hiperfun\u00e7\u00e3o, assim ser\u00e1 um paciente que ter\u00e1 altera\u00e7\u00f5es no hemograma de rotina, como anemias, e queda das plaquetas.<\/p><p>Um f\u00edgado aumentado, leva altera\u00e7\u00e3o da sua fun\u00e7\u00e3o, o que a longo prazo pode levar a fibrose do tecido hep\u00e1tico e assim maior risco de doen\u00e7as hep\u00e1ticas (cirrose, neoplasias)<\/p><p>Quando pensamos na hem\u00f3lise, devemos lembrar que a quebra maci\u00e7a de hem\u00e1cias causa libera\u00e7\u00e3o de bilirrubinas (tom amarelado de pele e olhos), essa bilirrubina livre pode se acumular em 2 locais e assim formar c\u00e1lculos (pedras): ves\u00edcula biliar e rins. Como complica\u00e7\u00e3o da forma\u00e7\u00e3o de pedras, podemos ter obstru\u00e7\u00e3o no ducto do p\u00e2ncreas, levando a quadros de pancreatite, hidronefrose (aumento de tamanho do rim), quadros frequentes de<\/p><p>As restri\u00e7\u00f5es, para muitos pais e familiares s\u00e3o dif\u00edceis, a pr\u00e1tica mostra que essa dificuldade se deve mais ao fato de restringir os corantes, mas \u00e9 um pre\u00e7o pequeno pela seguran\u00e7a dos pacientes portadores.<\/p><p>Devemos ter sempre com os documentos do paciente, c\u00f3pia da lista, s\u00f3 seguindo a lista de restri\u00e7\u00f5es n\u00e3o enfrentaremos todas as complica\u00e7\u00f5es descritas. Portanto seguir a lista \u00e9 melhor tratamento\/preven\u00e7\u00e3o para os portadores de defici\u00eancia de G6PD!!!!<\/p><p>Dr S\u00e9rgio Augusto Perlamagna \u00e9 Hematologista Pediatra e colunista do Blog<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6b9ac7c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6b9ac7c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ec195fb\" data-id=\"ec195fb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c819107 elementor-widget elementor-widget-text-editor\" data-id=\"c819107\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3>Atendimentos:<\/h3><h4>Centro M\u00e9dico Hospital Assun\u00e7\u00e3o:<\/h4><p>Avenida \u00c1lvaro Guimar\u00e3es, 3003 S\u00e3o Bernado do Campo<\/p><p>Agendamento: 3003-3230<\/p><h4>Clinica Ped:<\/h4><p class=\"_aacl _aaco _aacu _aacx _aad6 _aade\">Rua: Francisco Marengo n\u00b01439, Tatuap\u00e9, S\u00e3o Paulo<\/p><p>Agendamento: (11) 2941-6047<\/p><p>Whatsapp: (11) 96635-4712<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-440aabd elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"440aabd\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5008f55\" data-id=\"5008f55\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3756b0d elementor-widget elementor-widget-image\" data-id=\"3756b0d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"400\" height=\"200\" src=\"https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/deficiencia-de-g6pd-34-1.png\" class=\"attachment-large size-large wp-image-2673\" alt=\"\" srcset=\"https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/deficiencia-de-g6pd-34-1.png 400w, https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/deficiencia-de-g6pd-34-1-300x150.png 300w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Uma d\u00favida muito frequente para os pais de portadores da Defici\u00eancia de&nbsp; G6PD \u00e9: se eu n\u00e3o seguir as restri\u00e7\u00f5es [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":2579,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[185,27,184],"tags":[29,32,31,30],"class_list":["post-2578","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-colunista-hemato-pediatra","category-g6pd","category-papo-profissional","tag-deficiencia-de-g6pd","tag-dicas-g6pd","tag-g6pd-informacao","tag-maes-g6pd"],"uagb_featured_image_src":{"full":["https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/b2.jpg",1170,700,false],"thumbnail":["https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/b2-150x150.jpg",150,150,true],"medium":["https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/b2-300x179.jpg",300,179,true],"medium_large":["https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/b2-768x459.jpg",768,459,true],"large":["https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/b2-1024x613.jpg",1024,613,true],"1536x1536":["https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/b2.jpg",1170,700,false],"2048x2048":["https:\/\/cafeprosaedicas.com.br\/wp-content\/uploads\/2023\/01\/b2.jpg",1170,700,false]},"uagb_author_info":{"display_name":"Dr S\u00e9rgio Augusto Perlamagna","author_link":"https:\/\/cafeprosaedicas.com.br\/?author=3"},"uagb_comment_info":0,"uagb_excerpt":"Uma d\u00favida muito frequente para os pais de portadores da Defici\u00eancia de&nbsp; G6PD \u00e9: se eu n\u00e3o seguir as restri\u00e7\u00f5es [&hellip;]","_links":{"self":[{"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=\/wp\/v2\/posts\/2578","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2578"}],"version-history":[{"count":5,"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=\/wp\/v2\/posts\/2578\/revisions"}],"predecessor-version":[{"id":3343,"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=\/wp\/v2\/posts\/2578\/revisions\/3343"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=\/wp\/v2\/media\/2579"}],"wp:attachment":[{"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2578"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2578"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cafeprosaedicas.com.br\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2578"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}